DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and Kirrel1

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_006232737.1	Gene:	Kirrel1 / 310695	RGDID:	727883	Length:	805	Species:	Rattus norvegicus

Alignment Length:	339	Identity:	80/339 - (23%)
Similarity:	134/339 - (39%)	Gaps:	65/339 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 AISLDSVLSAPVISQISKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMR---- 83
            :|.|| |...|.::...:......|:.|.|.|                 ::..|..:|..|
  Rat   246 SIELD-VHHPPTVTLSIEPQTVLEGERVIFTC-----------------QATANPEILGYRWAKG 292

  Fly    84 --NILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVL--VSATEKVTKKLSLQIK 144
              .|....:.||...|.         |:|..:        |..|:|.  |.:| .|:..:::..
  Rat   293 GFLIEDAHESRYETNVD---------YSFFTE--------PVSCEVYNKVGST-NVSTLVNVHF- 338

  Fly   145 TPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAV------MPAGGHLLAE----- 198
            .|.::.  .||.|....|.::.|||...|.|..|::|.::.:.:      .|...:|.|:
  Rat   339 APRIVV--YPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMGPRLPGSPPEANLSAQVLSNS 401

  Fly   199 PTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQG 263
            ..|.::||.:.|.|.|.|.|........:|.:.:.|...|.|:.:..:.| :.....::||.:..
  Rat   402 NQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFA-VRGDGGKVECFIGS 465

  Fly   264 YPAPTVV---WHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYY-CNATNKLGHA 324
            .|.|..:   |.:|.:.:.:...:.|..|.|.|| ..|.|.|::|.|.||..:| |.|.|..|..
  Rat   466 TPPPDRIAWAWKENFLEVGTLERYTVERTNSGSG-VLSTLTINNVMEADFQTHYNCTAWNSFGPG 529

  Fly   325 DARLHLFQ-TVIPV 337
            .|.:.|.: .|:||
  Rat   530 TAIIQLEEREVLPV 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	20/117 (17%)
		Ig	37..127	CDD:299845	15/95 (16%)
		IG_like	154..234	CDD:214653	23/90 (26%)
		IGc2	161..223	CDD:197706	19/72 (26%)
		I-set	254..330	CDD:254352	24/79 (30%)
		IGc2	254..322	CDD:197706	22/71 (31%)
Kirrel1	XP_006232737.1	I-set	54..148	CDD:254352
		Ig	57..148	CDD:299845
		Ig2_KIRREL3-like	170..251	CDD:143236	3/5 (60%)
		I-set	255..336	CDD:254352	20/115 (17%)
		Ig_2	259..337	CDD:290606	19/112 (17%)
		Ig_2	340..437	CDD:290606	24/98 (24%)
		IG_like	346..437	CDD:214653	23/90 (26%)
		Ig5_KIRREL3	439..536	CDD:143306	27/98 (28%)
		IG_like	451..536	CDD:214653	25/86 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900