DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and sdk

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001284756.1	Gene:	sdk / 31017	FlyBaseID:	FBgn0021764	Length:	2265	Species:	Drosophila melanogaster

Alignment Length:	326	Identity:	76/326 - (23%)
Similarity:	133/326 - (40%)	Gaps:	57/326 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ISLDSVLSAPVISQISKDVVASVGDSVEFNC-TVEEVGQLSVS-WAKRPSESDTNSVV-LSMRNI 85
            ::.|:.|   ||.::..|      |:..|.| .:.|.|:.|.| |.:..:::..|.|. |:...|
  Fly   412 LNTDNTL---VIKKLILD------DAAMFQCLAINEAGENSASTWLRVKTKTAKNRVKRLAQPRI 467

  Fly    86 LSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIA 150
            |.:......:...:|.::||            ||                 ::...:..:.|::
  Fly   468 LRVRASHAGLGSEKGSESGS------------SD-----------------RRKEFRFASAPIM- 502

  Fly   151 ENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGG--HLLAEPTLRIRSVHRMDRGG 213
            |..|::....:|::..::|.|.|.|.|.|:|......::....  .:|....|.|.::..:|.|.
  Fly   503 ELPPQNVTALDGKDATISCRAVGSPNPNITWIYNETQLVDISSRVQILESGDLLISNIRSVDAGL 567

  Fly   214 YYCIAQNGEGQPDKRLIRVEVEFRPQIAVQRP-KIAQMVSHSAELECSVQGYPAP--TVVWHKNG 275
            |.|:..|..|.. |....:.|..|.|| :|.| ....::..:|.|:|.|...|:.  .:.|::.|
  Fly   568 YICVRANEAGSV-KGEAYLSVLVRTQI-IQPPVDTTVLLGLTATLQCKVSSDPSVPYNIDWYREG 630

  Fly   276 VPLQSSRHHEVANTASSSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHAD--ARLHLFQTVIPVP 338
               |||.  .::|:..........|.|.:|...|.|.|.|..|:..|:..  |||.:.:...| |
  Fly   631 ---QSST--PISNSQRIGVQADGQLEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFP-P 689

  Fly   339 S 339
            |
  Fly   690 S 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	21/112 (19%)
		Ig	37..127	CDD:299845	19/92 (21%)
		IG_like	154..234	CDD:214653	19/81 (23%)
		IGc2	161..223	CDD:197706	16/63 (25%)
		I-set	254..330	CDD:254352	23/79 (29%)
		IGc2	254..322	CDD:197706	19/69 (28%)
sdk	NP_001284756.1	Ig	71..157	CDD:299845
		I-set	72..150	CDD:254352
		Ig	172..245	CDD:299845
		IG_like	280..356	CDD:214653
		Ig	280..343	CDD:299845
		IG_like	375..450	CDD:214653	13/46 (28%)
		Ig	378..447	CDD:143165	12/43 (28%)
		Ig	506..587	CDD:299845	19/81 (23%)
		IG_like	506..587	CDD:214653	19/81 (23%)
		I-set	592..682	CDD:254352	27/95 (28%)
		Ig	595..682	CDD:299845	25/91 (27%)
		FN3	686..789	CDD:238020	3/6 (50%)
		FN3	798..893	CDD:238020
		FN3	901..1005	CDD:238020
		fn3	1011..1094	CDD:278470
		FN3	1108..1202	CDD:238020
		FN3	1210..1308	CDD:238020
		fn3	1317..1402	CDD:278470
		FN3	1415..1507	CDD:238020
		FN3	1513..1608	CDD:238020
		fn3	1617..1708	CDD:278470
		FN3	1722..1823	CDD:238020
		FN3	1828..1920	CDD:238020
		FN3	1927..2016	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810