DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ama and Ncam2

DIOPT Version :9

Sequence 1:NP_731114.2 Gene:Ama / 40831 FlyBaseID:FBgn0000071 Length:341 Species:Drosophila melanogaster
Sequence 2:NP_981954.2 Gene:Ncam2 / 288280 RGDID:1303131 Length:837 Species:Rattus norvegicus


Alignment Length:296 Identity:75/296 - (25%)
Similarity:113/296 - (38%) Gaps:41/296 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 GDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFR 111
            |:..|..|.|......:|||.....|            :.::||.|:.|....         ..:
  Rat   129 GEDAEVVCRVSSSPAPAVSWLYHNEE------------VTTIPDNRFAVLANN---------NLQ 172

  Fly   112 IQNIEVSDMGPYECQVLVSATEKVT-KKLSLQIKTPPVIAENTPKSTLVTE-GQNLELTCHANGF 174
            |.||..||.|.|.|:..|.|..::. :.:.:.:..||.|...........| |:.:.|||.|:|.
  Rat   173 ILNINKSDEGIYRCEGR
VEARGEIDFRDIIVIVNVPPAIVMPQKSFNATAERGEEMTLTCKASGS 237

  Fly   175 PKPTISWAREHNAVMPAGGHLL--AEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFR 237
            |.|.|||.|....:.....::|  :...|.:|::...|.|.|.|.|.|..|:..|:...      
  Rat   238 PDPAISWFRNGKLIEENEKYILKGSNTELTVRNIINKDGGSYVCKATNKAGEDQKQAFL------ 296

  Fly   238 PQIAVQRPKIAQMVSHSAE------LECSVQGYPAPTVVWHK--NGVPLQSSRHHEVANTASSSG 294
             |:.|| |.|.|:.:.:..      |.|..:|.|.|.:.|.:  :||..................
  Rat   297 -QVFVQ-PHILQLKNETTSENGHVTLICEAEGEPVPEITWKRAIDGVTFSEGDKSPDGRIEVKGQ 359

  Fly   295 TTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHL 330
            ...|.|.|..|...|.|.|.|.|.:::|.....:||
  Rat   360 HGRSSLHIRDVKLSDSGRYDCEAASRIGGHQRSMHL 395

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AmaNP_731114.2 I-set 33..143 CDD:254352 22/96 (23%)
Ig 37..127 CDD:299845 20/79 (25%)
IG_like 154..234 CDD:214653 24/82 (29%)
IGc2 161..223 CDD:197706 22/64 (34%)
I-set 254..330 CDD:254352 18/83 (22%)
IGc2 254..322 CDD:197706 17/75 (23%)
Ncam2NP_981954.2 IgI_1_NCAM-2 21..113 CDD:409452
Ig strand B 38..42 CDD:409452
Ig strand C 50..54 CDD:409452
Ig strand E 76..80 CDD:409452
Ig strand F 90..95 CDD:409452
Ig strand G 104..107 CDD:409452
IGc2 128..189 CDD:197706 20/80 (25%)
Ig strand B 130..139 CDD:409353 2/8 (25%)
Ig strand C 145..153 CDD:409353 3/7 (43%)
Ig strand C' 156..159 CDD:409353 0/2 (0%)
Ig strand D 162..167 CDD:409353 2/4 (50%)
Ig strand E 168..175 CDD:409353 1/15 (7%)
IgI_1_MuSK 209..298 CDD:409562 26/95 (27%)
Ig strand B 228..232 CDD:409562 1/3 (33%)
Ig strand C 241..245 CDD:409562 2/3 (67%)
Ig strand E 264..268 CDD:409562 1/3 (33%)
Ig strand F 278..283 CDD:409562 2/4 (50%)
Ig strand G 291..294 CDD:409562 1/2 (50%)
Ig 300..397 CDD:416386 25/97 (26%)
Ig strand A 300..305 CDD:409353 3/5 (60%)
Ig strand A' 309..313 CDD:409353 0/3 (0%)
Ig strand B 317..325 CDD:409353 2/7 (29%)
Ig strand C 331..337 CDD:409353 1/5 (20%)
Ig strand C' 340..343 CDD:409353 2/2 (100%)
Ig strand D 353..359 CDD:409353 0/5 (0%)
Ig strand E 362..368 CDD:409353 2/5 (40%)
Ig strand F 376..384 CDD:409353 4/7 (57%)
Ig strand G 387..397 CDD:409353 3/9 (33%)
Ig_3 401..479 CDD:404760
Ig strand B 418..422 CDD:409353
Ig strand C 431..435 CDD:409353
Ig strand E 458..462 CDD:409353
Ig strand F 472..477 CDD:409353
Ig strand G 486..489 CDD:409353
FN3 496..588 CDD:238020
fn3 594..678 CDD:394996
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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