Protein Alignment Ama and NEGR1

DIOPT Version :9

• Sequence 1: NP_731114.2
• Gene: Ama / 40831
• FlyBaseID: FBgn0000071
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 87/285 - (30%)
• Similarity: 134/285 - (47%)
• Gaps: 26/285 - (9%)

  Fly    47 GDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFR 111
            ||:....|.:|: |....:|..|      :|::.:..:..|: |.|.:::.     .....|:.:
Human    53 GDTAVLRCYLED-GASKGAWLNR------SSIIFAGGDKWSV-DPRVSIST-----LNKRDYSLQ 104

  Fly   112 IQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPK 176
            |||::|:|.|||.|.|....|.: |.::.|.::.||.|.:.:...| |.||.|:.|||.|.|.|:
Human   105 IQNVDVTDDGPYTCSVQTQHTPR-TMQVHLTVQVPPKIYDISNDMT-VNEGTNVTLTCLATGKPE 167

  Fly   177 PTISWAREHNAVMPAGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIA 241
            |:|||..    :.|:.........|.|..:.|...|.|.|.|:|....||.|.::|.|.|.|  .
Human   168 PSISWRH----ISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAP--T 226

  Fly   242 VQRPKIAQMV-SHSAELECSVQGYPAPTVVWHKNGVPLQSSRHHEVANTASSSGTTTSVLRIDSV 305
            :|..|...:. ..|..:.|...|.|.|...|:|....|.:.:...:....|    |.|:|.:.:|
Human   227 IQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFS----TRSILTVTNV 287

  Fly   306 GEEDFGDYYCNATNKLGHADARLHL 330
            .:|.||:|.|.|.||||..:|.|.|
Human   288 TQEHFGNYTCVAANKLGTTNASLPL 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	25/95 (26%)
		Ig	37..127	CDD:299845	21/79 (27%)
		IG_like	154..234	CDD:214653	28/79 (35%)
		IGc2	161..223	CDD:197706	22/61 (36%)
		I-set	254..330	CDD:254352	25/75 (33%)
		IGc2	254..322	CDD:197706	21/67 (31%)
NEGR1	NP_776169.2	IG	47..135	CDD:214652	25/95 (26%)
		IGc2	152..210	CDD:197706	22/61 (36%)
		Ig_3	225..301	CDD:372822	22/81 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I4716
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42757
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.900