DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ama and Kirrel2

DIOPT Version :9

Sequence 1:NP_731114.2 Gene:Ama / 40831 FlyBaseID:FBgn0000071 Length:341 Species:Drosophila melanogaster
Sequence 2:NP_766486.1 Gene:Kirrel2 / 243911 MGIID:2442334 Length:700 Species:Mus musculus


Alignment Length:337 Identity:88/337 - (26%)
Similarity:132/337 - (39%) Gaps:83/337 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 AISLDSVLSAPVISQISKDVVASVGDSVEFNCTVEEVGQLSVS---WAKRPSESDTNSVVLSMRN 84
            |::| |:...|:::..::......|:.|.|.|  :...|..|:   |||      ..|.||..| 
Mouse   215 AVTL-SLQYPPMVTLSAEPQTVQEGEKVTFLC--QATAQPPVTGYRWAK------GGSPVLGAR- 269

  Fly    85 ILSLPDQRYNVTVTEGPKTG-SAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPV 148
                           ||:.. .|..||..:        |..|:| .:|.....:..:|::...|:
Mouse   270 ---------------GPRLEVVADATFLTE--------PVSCEV-SNAVGSANRSTALEVLYGPI 310

  Fly   149 IAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAEPTLRIRSVHRMDRGG 213
            : :..|||..|..|::...:|...|.|.|.|:|.|...:.:.:.|     ||||:.||...|.|.
Mouse   311 L-QAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMGGSQVLSSG-----PTLRLPSVALEDAGD 369

  Fly   214 YYCIAQN-----GEGQPDKRLIRVEVEFRPQIAVQRPKIAQMVSHSAELECSVQGYPAP-TVVWH 272
            |.|.|:.     |.|:...||   .|...|.:...:|..| .:...|.|:|.|...||| :|||.
Mouse   370 YVCRAEPRRTGLGGGKAQARL---TVNAPPVVTALQPAPA-FLRGPARLQCVVFASPAPDSVVWS 430

  Fly   273 KNGVPLQSSRHHEVANTASSSGT------------------TTSVLRIDSVGEEDF-GDYYCNAT 318
            .:...|:          |.|.|.                  ..|||.|....|.|| ..:.|:|.
Mouse   431 WDEGFLE----------AGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSAR 485

  Fly   319 NKLGHADARLHL 330
            |:||....::||
Mouse   486 NRLGEGRVQIHL 497

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AmaNP_731114.2 I-set 33..143 CDD:254352 24/113 (21%)
Ig 37..127 CDD:299845 20/93 (22%)
IG_like 154..234 CDD:214653 28/84 (33%)
IGc2 161..223 CDD:197706 21/66 (32%)
I-set 254..330 CDD:254352 26/95 (27%)
IGc2 254..322 CDD:197706 24/87 (28%)
Kirrel2NP_766486.1 IG 27..116 CDD:214652
Ig 122..220 CDD:416386 2/5 (40%)
Ig strand A 123..126 CDD:409353
Ig strand A' 129..133 CDD:409353
Ig strand B 140..147 CDD:409353
Cell attachment site. /evidence=ECO:0000255 146..148
Ig strand C 153..158 CDD:409353
Ig strand C' 161..163 CDD:409353
Ig strand D 166..173 CDD:409353
Ig strand E 180..188 CDD:409353
Ig strand F 197..205 CDD:409353
Ig strand G 211..217 CDD:409353 1/1 (100%)
Ig_3 223..292 CDD:404760 22/101 (22%)
Ig strand B 241..245 CDD:409353 2/3 (67%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 272..275 CDD:409353 0/2 (0%)
Ig strand F 281..290 CDD:409353 3/16 (19%)
Ig strand G 298..301 CDD:409353 0/2 (0%)
Ig 315..392 CDD:416386 28/84 (33%)
Ig strand A' 316..321 CDD:409353 2/4 (50%)
Ig strand B 324..333 CDD:409353 1/8 (13%)
Ig strand C 339..343 CDD:409353 1/3 (33%)
Ig strand C' 346..348 CDD:409353 0/1 (0%)
Ig strand D 351..354 CDD:409353 0/2 (0%)
Ig strand E 355..360 CDD:409353 4/4 (100%)
Ig strand F 368..376 CDD:409353 4/7 (57%)
Ig strand G 382..392 CDD:409353 4/12 (33%)
Ig 394..498 CDD:416386 31/115 (27%)
Ig strand A 395..399 CDD:409353 1/3 (33%)
Ig strand A' 401..404 CDD:409353 0/2 (0%)
Ig strand B 412..419 CDD:409353 3/6 (50%)
Ig strand C 426..431 CDD:409353 3/4 (75%)
Ig strand C' 433..436 CDD:409353 0/2 (0%)
Ig strand D 444..451 CDD:409353 0/6 (0%)
Ig strand E 461..468 CDD:409353 3/6 (50%)
Ig strand F 479..486 CDD:409353 2/6 (33%)
Ig strand G 489..496 CDD:409353 1/6 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..576
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 671..700
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.