DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and zig-3

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_509336.1	Gene:	zig-3 / 192088	WormBaseID:	WBGene00006980	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	262	Identity:	58/262 - (22%)
Similarity:	94/262 - (35%)	Gaps:	58/262 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLIGLIFCLAISLDSVLSAPVISQIS-----------------------KDVVASVGDSVEFNCT 55
            |||.:....|||...:.|..:.:.:|                       :|...|.|:||...|.
Worm     2 LLICISVLAAISAHPLSSGEMRAAVSNLVREIDSTHLTTKPSLKIIEGLEDNTVSTGESVTLRCD 66

  Fly    56 VEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYT--FRIQNIEVS 118
            |.......:.|.|.......:..:.....:|:          ..||...|.|.|  ::|....:.
Worm    67 VLSTPTGVIYWEKDGQRIQGDKELNVFEKVLN----------AMGPTVESGIITSSYQIPCANLH 121

  Fly   119 DMGPYECQVLVSATEKVTKKLSLQIKTPPVIAENTPKS----TLVTEGQ-NLE-----LTCHANG 173
            .:|.|:| |..:..:.|.....:.::...|..::|.:|    |:.||.: .|:     |.|.|:
Worm   122 HIGSYKC-VATNGHDTVESSAKISVEGQTVKCKSTRRSAPVITMSTESRFELQDNAATLICRAD- 184

  Fly   174 FPKPTISWAREHNAVMPAGG--HLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQ--------PDKR 228
             .:...:|..|...:....|  .||....|.||.:...|.|.|:|||.|..|:        |.|:
Worm   185 -RRANWNWMFEDKKIDFDSGRYELLPSGDLLIRKIQWSDMGSYFCIAHNKYGESRGETFLYPTKK 248

  Fly   229 LI 230
            .|
Worm   249 HI 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	22/134 (16%)
		Ig	37..127	CDD:299845	20/114 (18%)
		IG_like	154..234	CDD:214653	27/97 (28%)
		IGc2	161..223	CDD:197706	20/69 (29%)
		I-set	254..330	CDD:254352
		IGc2	254..322	CDD:197706
zig-3	NP_509336.1	I-set	45..145	CDD:254352	21/110 (19%)
		Ig	61..142	CDD:143165	17/91 (19%)
		IG_like	177..244	CDD:214653	19/68 (28%)
		Ig	<191..237	CDD:299845	16/45 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900