Protein Alignment Ama and wrk-1

DIOPT Version :10

• Sequence 1: NP_731114.2
• Gene: Ama / 40831
• FlyBaseID: FBgn0000071
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_001024651.1
• Gene: wrk-1 / 181093
• WormBaseID: WBGene00006942
• Length: 452
• Species: Caenorhabditis elegans
• Alignment Length: 366
• Identity: 95/366 - (25%)
• Similarity: 154/366 - (42%)
• Gaps: 71/366 - (19%)

  Fly     9 MARLRLLIGLIFCLAISLDSVLSAPVISQI---SKDVVASVGDSVEFNCTVEEVGQLSVSWAKRP 70
            |..:.|::||           |.|...:||   ...::|..|:|:...|.||: ..:::.|.|
 Worm     2 MKLVLLILGL-----------LIASTSAQIRTKGGTLIAKEGESLTLRCEVED-PSVAIIWRK-- 52

  Fly    71 SESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVL---VSAT 132
                 |:.|:::.:.:......|.::: ||   .:::.|  |:.:|..:...|.|.:.   ||.|
 Worm    53 -----NTEVVAVDDEILDTYGGYEISM-EG---STSVLT--IKRVEPINSANYSCALAEPEVSVT 106

  Fly   133 ----EKVTKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCHA-NGFPKPTISWA---------- 182
                .:|.|...:.:|...||:.:|.........:||.:|||. .|.|||.:.|.
 Worm   107 FVIKVQVFKPTQVSVKPLVVISPDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAAKLPEDI 171

  Fly   183 -REHNAVMPAGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEV--------EFRP 238
             |||      ||..:.     |..|.:...|.|.|:|:|..|. |:..|.:.|        |.:|
 Worm   172 KREH------GGARIV-----ITEVKKHHAGKYNCLAENIAGS-DRATIDIHVAEPLQGEREEKP 224

  Fly   239 QIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNG--VPLQSSRHHEVANTASS-SGTTTSVL 300
            .:..:...|....:.:|...|:..|.|.|.|.|..||  :.....:..:.:.||.. :|.:.|.|
 Worm   225 WVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKFKKTSETAQRLNGYSKSTL 289

  Fly   301 RIDSVGEEDFGDYYCNATNKLGHADARLHLFQTVIPVPSLS 341
            .:..:.||.||||.|..:||||...|.:|:.....| |.||
 Worm   290 TVGDISEEAFGDYACRISNKLGSVTAVVHVSGRPGP-PQLS 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:400151	25/119 (21%)
		Ig strand B	50..54	CDD:409353	0/3 (0%)
		Ig strand C	63..68	CDD:409353	1/4 (25%)
		Ig strand E	101..112	CDD:409353	1/10 (10%)
		Ig strand F	122..127	CDD:409353	2/4 (50%)
		Ig strand G	136..139	CDD:409353	1/2 (50%)
		Ig_3	146..220	CDD:464046	24/85 (28%)
		I-set	254..330	CDD:400151	26/78 (33%)
		Ig strand B	255..259	CDD:409353	1/3 (33%)
		Ig strand C	268..272	CDD:409353	1/3 (33%)
		Ig strand E	298..302	CDD:409353	2/3 (67%)
		Ig strand F	312..317	CDD:409353	3/4 (75%)
wrk-1	NP_001024651.1	IG_like	25..113	CDD:214653	21/101 (21%)
		Ig strand B	35..39	CDD:409353	0/3 (0%)
		Ig strand C	47..51	CDD:409353	0/3 (0%)
		Ig strand E	77..83	CDD:409353	1/7 (14%)
		Ig strand F	93..98	CDD:409353	2/4 (50%)
		Ig strand G	104..107	CDD:409353	1/2 (50%)
		Ig	136..212	CDD:472250	25/87 (29%)
		Ig strand B	143..147	CDD:409353	1/3 (33%)
		Ig strand C	157..161	CDD:409353	0/3 (0%)
		Ig strand E	178..182	CDD:409353	0/8 (0%)
		Ig strand F	192..197	CDD:409353	2/4 (50%)
		Ig	235..319	CDD:472250	26/83 (31%)
		Ig strand C	254..258	CDD:409353	1/3 (33%)
		Ig strand E	278..291	CDD:409353	4/12 (33%)
		Ig strand F	301..306	CDD:409353	3/4 (75%)
		Ig strand G	314..317	CDD:409353	1/2 (50%)