DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and zig-4

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	232	Identity:	52/232 - (22%)
Similarity:	83/232 - (35%)	Gaps:	51/232 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 TEKVTKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISW---------AREHN- 186
            |..:|....::|..|       .:|.|:..|:..:|.|.....|..||.|         :.|.|
Worm    37 TNYLTSPAKIKIVAP-------LESALIPGGETYQLRCDIMSTPAATIHWKFNGKLIQGSNELNV 94

  Fly   187 ---------AVMPAGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVE------- 235
                     |::..|   :....|.|:.....:.|.|.|:..||. |..:.:..||:|
Worm    95 EEKLLNFGKAIVDTG---IVASILTIQCPSAENSGTYSCVGYNGH-QTIETVAEVEIEGEASGCR 155

  Fly   236 ----FRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHKNGVPLQSSRHHEVANTASSSGTT 296
                ..|:|........:|..:.|.|.|  :.......||..|...::::...    |..|:|.
Worm   156 SNHKSAPEIVFWTDSRFEMTGNVATLVC--RANQQVDWVWMSNDELVKNNDKF----TVLSNGD- 213

  Fly   297 TSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLFQT 333
               |.|.::..:|.|.|.|.|.|:.|.|.....|:.|
Worm   214 ---LVIKNIVWDDMGTYTCIARNQFGEARQETFLYPT 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	2/10 (20%)
		Ig	37..127	CDD:299845
		IG_like	154..234	CDD:214653	22/98 (22%)
		IGc2	161..223	CDD:197706	18/80 (23%)
		I-set	254..330	CDD:254352	19/75 (25%)
		IGc2	254..322	CDD:197706	17/67 (25%)
zig-4	NP_509335.1	I-set	47..147	CDD:254352	24/110 (22%)
		Ig	65..144	CDD:143165	18/82 (22%)
		IG_like	176..245	CDD:214653	19/78 (24%)
		Ig	<193..238	CDD:299845	14/52 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900