DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ama and Opcml

DIOPT Version :9

Sequence 1:NP_731114.2 Gene:Ama / 40831 FlyBaseID:FBgn0000071 Length:341 Species:Drosophila melanogaster
Sequence 2:XP_017450901.1 Gene:Opcml / 116597 RGDID:620635 Length:354 Species:Rattus norvegicus


Alignment Length:301 Identity:84/301 - (27%)
Similarity:128/301 - (42%) Gaps:40/301 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 DVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNSVVLSMRNILSLPDQRYNVTVTEGPKTGS 105
            :|....|:|....||::: ....|:|..|       |.:|...|.....|.|..:.|....:   
  Rat    44 NVTVRQGESATLRCTIDD-RVTRVAWLNR-------STILYAGNDKWSIDPRVIILVNTPTQ--- 97

  Fly   106 AIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQIKTPPVIAENTPKSTLVTEGQNLELTCH 170
              |:..|||::|.|.|||.|.|......| |.::.|.::.||.|. |......|.||.::.|.|.
  Rat    98 --YSIMIQNVDVYDEGPYTCSVQTDNHPK-TSRVHLIVQVPPQIM-NISSDITVNEGSSVTLLCL 158

  Fly   171 ANGFPKPTISWAREHNAVMPAGGHLLAEPTLRIRSVHRMDRGGYYCIAQNGEGQPDKRLIRVEVE 235
            |.|.|:||::|  .|.:|....|.:..:..|.|..:.|...|.|.|.|.|....||.|.:::.|.
  Rat   159 AIGRPEPTVTW--RHLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVN 221

  Fly   236 FRPQIAVQRPKIAQMVSHSAELECSVQGYPAPTVVWHK---------NGVPLQSSRHHEVANTAS 291
            :.|.|: :.......|.....|.|.....|.....|.|         :||.:::...        
  Rat   222 YPPYIS-KAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGVRIENKGR-------- 277

  Fly   292 SSGTTTSVLRIDSVGEEDFGDYYCNATNKLGHADARLHLFQ 332
                 .|.|...:|.|:|:|:|.|.||||||:.:|.:.|::
  Rat   278 -----ISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYE 313

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AmaNP_731114.2 I-set 33..143 CDD:254352 28/101 (28%)
Ig 37..127 CDD:299845 24/85 (28%)
IG_like 154..234 CDD:214653 25/79 (32%)
IGc2 161..223 CDD:197706 21/61 (34%)
I-set 254..330 CDD:254352 22/84 (26%)
IGc2 254..322 CDD:197706 19/76 (25%)
OpcmlXP_017450901.1 Ig 44..132 CDD:416386 28/101 (28%)
Ig strand A' 44..49 CDD:409353 1/4 (25%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 0/4 (0%)
FR2 64..70 CDD:409353 2/5 (40%)
Ig strand C 64..70 CDD:409353 2/5 (40%)
CDR2 71..83 CDD:409353 4/18 (22%)
Ig strand C' 72..76 CDD:409353 1/3 (33%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 13/38 (34%)
Ig strand D 87..94 CDD:409353 2/6 (33%)
Ig strand E 97..103 CDD:409353 1/10 (10%)
Ig strand F 110..118 CDD:409353 4/7 (57%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 3/9 (33%)
FR4 125..132 CDD:409353 2/6 (33%)
Ig_3 135..206 CDD:404760 25/73 (34%)
Ig strand A 135..138 CDD:409353 2/2 (100%)
Ig strand A' 144..148 CDD:409353 0/3 (0%)
Ig strand B 151..160 CDD:409353 2/8 (25%)
Ig strand C 165..170 CDD:409353 3/6 (50%)
Ig strand C' 171..174 CDD:409353 1/2 (50%)
Ig strand F 198..206 CDD:409353 4/7 (57%)
Ig_3 223..300 CDD:404760 19/90 (21%)
putative Ig strand A 224..230 CDD:409353 2/6 (33%)
Ig strand B 240..244 CDD:409353 1/3 (33%)
Ig strand C 253..257 CDD:409353 0/3 (0%)
Ig strand E 279..283 CDD:409353 2/3 (67%)
Ig strand F 293..298 CDD:409353 2/4 (50%)
Ig strand G 306..309 CDD:409353 1/2 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337172
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR42757
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
76.850

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