DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ama and iglon5

DIOPT Version :9

Sequence 1:	NP_731114.2	Gene:	Ama / 40831	FlyBaseID:	FBgn0000071	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	81/332 - (24%)
Similarity:	142/332 - (42%)	Gaps:	51/332 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ISLDSVLSAPVISQI-----------SKDVVASVGDSVEFNCTVEEVGQLSVSWAKRPSESDTNS 77
            :||.| |...:::|:           :.:...|.||:...:|.::: ....|:|..|      ::
Frog     8 VSLAS-LGIVMLAQVLFVQCTEFVPPADNYTVSQGDNATLSCLIDD-KVTRVAWLNR------SN 64

  Fly    78 VVLSMRNILSLPDQRYNVTVTEGPKTGSAIYTFRIQNIEVSDMGPYECQVLVSATEKVTKKLSLQ 142
            ::.:.::..|:..:...:|.|:..      |:..|.:::|:|.|.|.|. ..:..:..|.::.|.
Frog    65 ILYAGKDKWSIDSRVQLLTNTKSE------YSIVITHVDVADEGLYTCS-FQTEDKPHTSQVYLI 122

  Fly   143 IKTPPVIAENTPKSTLVTEGQNLELTCHANGFPKPTISWAREHNAVMPAGGHLLAEPTLRIRSVH 207
            ::.|..|. |...|..|.||.|:.|.|.|.|.|:|||:|.:........|      ..|.|..::
Frog   123 VQVPAKIV-NISSSVTVNEGSNVNLQCLAVGKPEPTITWQQLSEGFSSEG------ELLEITEIN 180

  Fly   208 RMDRGGYYCIAQNGEGQPDKRLIRVEVEFRPQIA----VQRPKIAQMVSHSAELECSVQGYPAPT 268
            |...|.|.|:..||...||.:.:::.|.:.|.|.    .|.|     |...|.|.|.....|...
Frog   181 RQQAGDYECVTSNGVSVPDTKKVQITVNYPPYITDVKNAQSP-----VGRPATLRCKAMAVPPAE 240

  Fly   269 VVWHKNGVPLQSSRHHEVANTASSSGTTT---SVLRIDSVGEEDFGDYYCNATNKLGHADARLHL 330
            ..|:|:      .:...::.|...|..|.   ||:...:|....:|:|.|.|:||||..::.|.|
Frog   241 FEWYKD------EKRRLISGTEGLSIKTESSWSVIVFSNVTSRHYGNYTCLASNKLGSFNSSLRL 299

  Fly   331 FQTVIPV 337
            .:...|:
Frog   300 LKPGDPL 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ama	NP_731114.2	I-set	33..143	CDD:254352	20/120 (17%)
		Ig	37..127	CDD:299845	18/100 (18%)
		IG_like	154..234	CDD:214653	25/79 (32%)
		IGc2	161..223	CDD:197706	21/61 (34%)
		I-set	254..330	CDD:254352	21/78 (27%)
		IGc2	254..322	CDD:197706	18/70 (26%)
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	19/105 (18%)
		IG_like	35..123	CDD:214653	19/101 (19%)
		Ig	126..207	CDD:299845	28/87 (32%)
		I-set	128..207	CDD:254352	27/85 (32%)
		I-set	210..299	CDD:254352	26/99 (26%)
		Ig	227..298	CDD:143165	20/76 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR42757
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020