DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bcd and Nos

DIOPT Version :9

Sequence 1:	NP_788587.1	Gene:	bcd / 40830	FlyBaseID:	FBgn0000166	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_523541.2	Gene:	Nos / 34495	FlyBaseID:	FBgn0011676	Length:	1349	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	61/249 - (24%)
Similarity:	88/249 - (35%)	Gaps:	81/249 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 STNVNGGQFFQQQQVHNHQQQLHHQGNHVPHQMQQQQQQAQQQQYHHFDFQQKQASACRVLVKDE 315
            |||.      ||||   .|||         .|:||||||.|||:     .|.:|.::.::..:..
  Fly    20 STNA------QQQQ---QQQQ---------QQLQQQQQQLQQQK-----AQTQQQNSRKIKTQAT 61

  Fly   316 PEADYNFNSSYYMRSGMSGATASASAVARGAASPGSEVYEPLTPKNDESPSLCGIGIGGPCAIAV 380
            |..:.|         |:.....:...   |.:||..||..|                ||    |.
  Fly    62 PTLNGN---------GLLSGNPNGGG---GDSSPSHEVDHP----------------GG----AQ 94

  Fly   381 GETEAADDM--DDGT----SKKTTLQILEP----LKGLDKSCD---DGSSDDMSTGIRALAGTGN 432
            | .:||..:  ..||    .|:.::....|    .:|.:.|..   |||...        :|:|.
  Fly    95 G-AQAAGGLPSSSGTPLRHHKRASISTASPPIRERRGTNTSIVVELDGSGSG--------SGSGG 150

  Fly   433 RGAAFAKFGKPSPPQGPQPPLGMGGVAMGESNQYQCTMDTIMQAYNPHRNAAGN 486
            .|....: |...||.|.....|.....:..|.:.|.....:.|.|   |:.||:
  Fly   151 GGVGVGQ-GAGCPPSGSCTASGKSSRELSPSPKNQQQPRKMSQDY---RSRAGS 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
bcd	NP_788587.1	Homeobox	106..153	CDD:278475
Nos	NP_523541.2	NOS_oxygenase_euk	216..624	CDD:238410
		CysJ	669..1323	CDD:223446
		Flavodoxin_1	673..863	CDD:278677
		Nitric_oxide_synthase	931..1328	CDD:99799
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.75	Normalized mean entropy	S1636
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.950