DRSC/TRiP Functional Genomics Resources

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Protein Alignment bcd and HOXD4

DIOPT Version :9

Sequence 1:NP_788587.1 Gene:bcd / 40830 FlyBaseID:FBgn0000166 Length:494 Species:Drosophila melanogaster
Sequence 2:NP_055436.2 Gene:HOXD4 / 3233 HGNCID:5138 Length:255 Species:Homo sapiens


Alignment Length:203 Identity:59/203 - (29%)
Similarity:79/203 - (38%) Gaps:42/203 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 QPPPDQNFYHHPLPHTHTHPHPHSHPHPHS------H------PHPHHQHPQLQLP-PQFRNPFD 54
            |||   ..|  |.|.....|...|.|.|.|      |      |..|:..|....| |....|..
Human    47 QPP---GLY--PRPDFGEQPFGGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAP 106

  Fly    55 LLFDERTGAINYNYIRPYLP---NQMPKPD-VFP------SEELPDSLVMRRPRRTRTTFTSSQI 109
            |     .||..|:...|..|   ..:.:|. |:|      ...:..:.....|:|:||.:|..|:
Human   107 L-----PGARAYSQSDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTGGEPKRSRTAYTRQQV 166

  Fly   110 AELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQSDQHKDQSYEGMPLSPGMK 174
            .|||:.|...||||..|..:::..|.|...|:||||:|||.:.|   ..||      :|.:.|..
Human   167 LELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWK---KDHK------LPNTKGRS 222

  Fly   175 QSDGDPPS 182
            .|.....|
Human   223 SSSSSSSS 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
bcdNP_788587.1 Homeobox 106..153 CDD:278475 20/46 (43%)
HOXD4NP_055436.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 31..127 24/89 (27%)
Antp-type hexapeptide 133..138 2/4 (50%)
Homeobox 157..210 CDD:306543 23/52 (44%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 212..255 6/25 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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