Protein Alignment bcd and HOXB2

DIOPT Version :9

• Sequence 1: NP_788587.1
• Gene: bcd / 40830
• FlyBaseID: FBgn0000166
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_002136.1
• Gene: HOXB2 / 3212
• HGNCID: 5113
• Length: 356
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 65/249 - (26%)
• Similarity: 87/249 - (34%)
• Gaps: 81/249 - (32%)

  Fly     4 PPPDQNFYHHPLPHTHTHPHPHSHPHPHSHPHPHHQHPQLQLPPQFRNPFDLLFDERTGAINYNY 68
            |||.:..:....|...|...|.|....       ...|.|..||.
Human    46 PPPFEQTFPSLQPGASTLQRPRSQKRA-------EDGPALPPPPP-------------------- 83

  Fly    69 IRPYLPNQMPKPDVFP-------------SEELPDSLVMRRP---------------------RR 99
              |.||...|.|: ||             |...|.......|                     ||
Human    84 --PPLPAAPPAPE-FPWMKEKKSAKKPSQSATSPSPAASAVPASGVGSPADGLGLPEAGGGGARR 145

  Fly   100 TRTTFTSSQIAELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQSDQHKDQSY 164
            .||.:|::|:.|||:.|...:||..||..:::|.|.|...|||:||:|||.:||.|: ||::..
Human   146 LRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT-QHREPP- 208

  Fly   165 EGMPLSPGMKQSDGDPPSLQTLSLGGGA---------------TPNALTPSPTP 203
            :|.|..||..:...||......|.||.:               .|.||:..|.|
Human   209 DGEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHPPEVVPGALSADPRP 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bcd	NP_788587.1	Homeobox	106..153	CDD:278475	20/46 (43%)
HOXB2	NP_002136.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..142		21/125 (17%)
		Antp-type hexapeptide	94..99		2/5 (40%)
		Homeobox	147..199	CDD:278475	23/51 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..240		14/44 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900