Protein Alignment bcd and HOXA2

DIOPT Version :9

• Sequence 1: NP_788587.1
• Gene: bcd / 40830
• FlyBaseID: FBgn0000166
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 100/442 - (22%)
• Similarity: 146/442 - (33%)
• Gaps: 173/442 - (39%)

  Fly    14 PLPHTHTHP--HPHSHP------HPHSHPHPHHQHP----QLQLPPQFRNPFDLLFDERTGAINY 66
            |.|...|.|  :|.|||      .|...|......|    .|| ||::
Human    49 PPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQ-PPEY----------------- 95

  Fly    67 NYIRPYLPNQ--MPKPDVFPSEELPDSLVMRRP-------------------RRTRTTFTSSQIA 110
                |::..:  ..|..:.|:.....:.....|                   ||.||.:|::|:.
Human    96 ----PWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLL 156

  Fly   111 ELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQSDQHKDQSYEG--MPLSPGM 173
            |||:.|...:||..||..:::|.|.|...|||:||:|||.:||.|:...::|:.||  ..|....
Human   157 ELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSE 221

  Fly   174 K-QSDGDPPSL--QTLSLGG------GAT--PNALTPSPTPSTPTAHMTEHYSESFNAYYNYNGG 227
            | :.|.:..:|  |.||:.|      |.|  .|||:....|:                      |
Human   222 KVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQQQAPN----------------------G 264

  Fly   228 HNHAQANRHMHMQYPSGGGPGPGSTNVNGGQFFQQQQVHNHQQQLHHQGNHVPHQMQQQQQQAQQ 292
            ||...      ..:|    ..|.::|....:.||            ||...||:.:....|.
Human   265 HNGDS------QSFP----VSPLTSNEKNLKHFQ------------HQSPTVPNCLSTMGQN--- 304

  Fly   293 QQYHHFDFQQKQASACRV-LVKDEPEA-------DYNFNSSYYMRSGMSGATASASAVARGAASP 349
                           |.. |..|.|||       |::..|:       ......:.||
Human   305 ---------------CGAGLNNDSPEALEVPSLQDFSVFST-------DSCLQLSDAV------- 340

  Fly   350 GSEVYEPLTPKNDESPSLCGIGIGGPCAIAVGETEAADDMDDGTSKKTTLQI 401
                          ||||.| .:..|..|      :||.:|..|...||:.:
Human   341 --------------SPSLPG-SLDSPVDI------SADSLDFFTDTLTTIDL 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bcd	NP_788587.1	Homeobox	106..153	CDD:278475	20/46 (43%)
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		13/44 (30%)
		Antp-type hexapeptide	94..99		1/25 (4%)
		Homeobox	147..200	CDD:395001	24/52 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		9/30 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279		6/53 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900