Protein Alignment bcd and Gbx1

DIOPT Version :10

• Sequence 1: NP_788587.1
• Gene: bcd / 40830
• FlyBaseID: FBgn0000166
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_056554.1
• Gene: Gbx1 / 231044
• MGIID: 95667
• Length: 418
• Species: Mus musculus
• Alignment Length: 311
• Identity: 68/311 - (21%)
• Similarity: 94/311 - (30%)
• Gaps: 130/311 - (41%)

  Fly     5 PPDQNFYHHPLPH---------THTHPHPH--------------------SHPHPHSHPHPHHQH 40
            |||.  |:.| |.         :.::|.|.                    :.|.|...||.....
Mouse   170 PPDA--YYGP-PELAAAAASTASRSNPEPAARRTDGALDAEELLPAREKVTEPPPPPPPHFSETF 231

  Fly    41 PQL------------QLPPQFRNPF--------------DLLFDERTGAINYNYIRPYLPNQM-- 77
            |.|            :|.|...:|.              |...|...|.          |..:
Mouse   232 PSLPAEGKVYSSDEEKLEPPAGDPAGSEQEEEGSGGDSEDSFLDSSAGG----------PGALLG 286

  Fly    78 PKPDVFPS------EELPDSLVMRRP----RRTRTTFTSSQIAELEQHFLQGRYLTAPRLADLSA 132
            |||.:..|      |..|.:..:..|    ||.||.|||.|:.|||:.|...:||:....:.::.
Mouse   287 PKPKLKGSPGTGAEEGTPVATGVTTPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAH 351

  Fly   133 KLALGTAQVKIWFKNRRRRHK-IQSDQHKDQSYEGMPLSPGMKQSDGDPPSLQTLSLGGGATPNA 196
            .|.|...||||||:|||.:.| |::.....:|              |:|.          ..|..
Mouse   352 ALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRS--------------GEPV----------RNPKI 392

  Fly   197 LTPSPTPSTPTAHMTEHYSESFNAYYNYNGGHNHAQANRHMHMQYPSGGGP 247
            :.|.|.                         |.:..|.|..|.|...|..|
Mouse   393 VVPIPV-------------------------HVNRFAVRSQHQQMEQGARP 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bcd	NP_788587.1	Homeodomain	106..153	CDD:459649	19/46 (41%)
Gbx1	NP_056554.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..320		22/115 (19%)
		Homeodomain	317..373	CDD:459649	25/55 (45%)