DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bcd and Hoxb4

DIOPT Version :9

Sequence 1:	NP_788587.1	Gene:	bcd / 40830	FlyBaseID:	FBgn0000166	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_034589.3	Gene:	Hoxb4 / 15412	MGIID:	96185	Length:	250	Species:	Mus musculus

Alignment Length:	189	Identity:	48/189 - (25%)
Similarity:	69/189 - (36%)	Gaps:	59/189 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AQPPPDQNFYHHPLPHTHTHPHPHSH---PHPHSHPHPHHQHPQLQLPPQFRNPFDLLFDERTGA 63
            :.|||.      |......||.| ||   ..|..:|.....|                    ...
Mouse   114 SSPPPP------PCAQNPLHPSP-SHSACKEPVVYPWMRKVH--------------------VST 151

  Fly    64 INYNYIRPYLPNQMPKPDVFPSEELPDSLVMRRPRRTRTTFTSSQIAELEQHFLQGRYLTAPRLA 128
            :|.||                        ....|:|:||.:|..|:.|||:.|...||||..|..
Mouse   152 VNPNY------------------------AGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRV 192

  Fly   129 DLSAKLALGTAQVKIWFKNRRRR----HKIQSDQHKDQSYEGMPLSPGMKQSDGDPPSL 183
            :::..|.|...|:||||:|||.:    ||:.:.:.:.....|....| ..:.:|.||:|
Mouse   193 EIAHALCLSERQIKIWFQNRRMKWKKDHKLPNTKIRSGGTAGAAGGP-PGRPNGGPPAL 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bcd	NP_788587.1	Homeobox	106..153	CDD:278475	20/50 (40%)
Hoxb4	NP_034589.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..133		8/25 (32%)
		Antp-type hexapeptide	140..145		1/4 (25%)
		Homeobox	164..218	CDD:395001	23/53 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..250		7/31 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900