Protein Alignment bcd and Hoxa2

DIOPT Version :10

• Sequence 1: NP_788587.1
• Gene: bcd / 40830
• FlyBaseID: FBgn0000166
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_036713.2
• Gene: Hoxa2 / 103690123
• RGDID: 11468112
• Length: 372
• Species: Rattus norvegicus
• Alignment Length: 443
• Identity: 104/443 - (23%)
• Similarity: 147/443 - (33%)
• Gaps: 179/443 - (40%)

  Fly    14 PLPHTHTHP--HPHSHP--------HPHSHPHPHHQHP----QLQLPPQFRNPFDLLFDERTGAI 64
            |.|...|.|  :|.|||        .|.|.|......|    .|| ||::
  Rat    49 PPPFEQTIPSLNPGSHPRQSAGAGGRPKSSPAGSRGSPVPARALQ-PPEY--------------- 97

  Fly    65 NYNYIRPYLPNQMPKPDVFPSEELPDSLVMRRP-------------------RRTRTTFTSSQIA 110
                  |:    |.:........||.:.....|                   ||.||.:|::|:.
  Rat    98 ------PW----MKEKKAAKKTALPPAAASTGPACLGHKESLEIADGSGGGSRRLRTAYTNTQLL 152

  Fly   111 ELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQSDQHKDQSYEG--MPLSPGM 173
            |||:.|...:||..||..:::|.|.|...|||:||:|||.:||.|:...::|:.||  ..|....
  Rat   153 ELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKFKNLEDSD 217

  Fly   174 K-QSDGDPPSL--QTLSLGG------GAT--PNALTPSPTPSTPTAHMTEHYSESFNAYYNYNGG 227
            | :.|.:..||  |.||:.|      |.|  .|||:....|:                      |
  Rat   218 KVEEDEEEKSLFEQALSVSGALLEREGYTFQQNALSQQQAPN----------------------G 260

  Fly   228 HNHAQANRHMHMQYPSGGGPGPGSTNVNGGQFFQQQQVHNHQQQLHHQGNHVPHQMQQQQQQAQQ 292
            ||...      ..:|    ..|.::|....:.||            ||...||:.:....|.
  Rat   261 HNGDS------QTFP----VSPLTSNEKNLKHFQ------------HQSPTVPNCLSTMGQN--- 300

  Fly   293 QQYHHFDFQQKQASACRV-LVKDEPEA-------DYN-FNSSYYMRSGMSGATASASAVARGAAS 348
                           |.. |..|.|||       |:| |::...::  :|.|.
  Rat   301 ---------------CGAGLNNDSPEALEVPSLQDFNVFSTDSCLQ--LSDAL------------ 336

  Fly   349 PGSEVYEPLTPKNDESPSLCGIGIGGPCAIAVGETEAADDMDDGTSKKTTLQI 401
                           ||||.| .:..|..|      :||..|..|...||:.:
  Rat   337 ---------------SPSLPG-SLDSPVDI------SADSFDFFTDTLTTIDL 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bcd	NP_788587.1	Homeodomain	106..153	CDD:459649	20/46 (43%)
Hoxa2	NP_036713.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..96		15/47 (32%)
		Antp-type hexapeptide	96..101		1/29 (3%)
		Homeodomain	140..196	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		9/30 (30%)