DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bcd and Hoxb2

DIOPT Version :9

Sequence 1:	NP_788587.1	Gene:	bcd / 40830	FlyBaseID:	FBgn0000166	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	XP_002727852.1	Gene:	Hoxb2 / 100361765	RGDID:	2319509	Length:	355	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	64/237 - (27%)
Similarity:	94/237 - (39%)	Gaps:	51/237 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PPPDQNFYHHPLPHTHTHPHPHSHPHPHSHP---HPHHQHPQLQLPPQF-----RNPFDLLFDER 60
            |||       |.|...|.|...........|   .|....|.|:.||..     ...|..:.:::
  Rat    44 PPP-------PPPLEQTFPSLQLGASTLQRPGSQKPAGDGPALRPPPPLPVAPPAPEFPWMKEKK 101

  Fly    61 TGAINYNYIRPYLPNQMPKPDV---------FPSE--ELPDSLVMRRPRRTRTTFTSSQIAELEQ 114
            :..      :|......|.|..         .||:  .||:| .....||.||.:|::|:.|||:
  Rat   102 SAK------KPSQSAATPSPAASSVRASGVGSPSDGPGLPES-GGSGSRRLRTAYTNTQLLELEK 159

  Fly   115 HFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQSDQHKDQSYEGMPLSPGMKQSDGD 179
            .|...:||..||..:::|.|.|...|||:||:|||.:||.|: ||::.. :|.|.....:...|:
  Rat   160 EFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQT-QHREPP-DGEPGGLSAQDDAGE 222

  Fly   180 PPSLQTLSLGGGAT----------------PNALTPSPTPST 205
            |....|:|.|..|:                |....|...|:|
  Rat   223 PAEEPTVSPGDVASHRLREACFLPAEAAQGPRGAPPPLPPAT 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bcd	NP_788587.1	Homeobox	106..153	CDD:278475	20/46 (43%)
Hoxb2	XP_002727852.1	Homeobox	146..198	CDD:278475	23/51 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900