Protein Alignment zen and nkx2.1

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_571851.1
• Gene: nkx2.1 / 81883
• ZFINID: ZDB-GENE-010404-1
• Length: 346
• Species: Danio rerio
• Alignment Length: 253
• Identity: 63/253 - (24%)
• Similarity: 87/253 - (34%)
• Gaps: 90/253 - (35%)

  Fly    91 KRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREP 155
            ::.|..|:..|:.|||..||...||....|..:|..:.|...||||||||.|.|.|:
Zfish   160 RKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR-------- 216

  Fly   156 KSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEAS 220
            ::..|::|.|.:|.  .|..::   ..|.||        |..:.|...:.||
Zfish   217 QAKDKVSQQQMQQD--NGSCQQ---QQQSPR--------RVAVPVLVKDGKP------------- 255

  Fly   221 TNNGMCSSADLSEILEHLAQTTAAPQVSTATSSTGTSTN-----------SASSSSSGHYSYNVD 274
                 |                   |.|:.|.:||...:           :.|.|.|.|.|..|.
Zfish   256 -----C-------------------QGSSHTPNTGVQNHHHQGGNVMFMTNTSLSMSQHQSQQVG 296

  Fly   275 LVLQSIKQDLEAAAQAWSKSKSAPILATQSWHPSSQSQVPTSVHAAPSMNLSWGEPAA 332
            ...||:.....||:.                 ||.|:|||...|    :|.|..|..|
Zfish   297 SAGQSLDLGQHAASP-----------------PSLQTQVPGLSH----LNSSGSEYGA 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	23/55 (42%)
nkx2.1	NP_571851.1	Homeodomain	160..216	CDD:459649	23/55 (42%)