Protein Alignment zen and nkx2.4b

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_571664.1
• Gene: nkx2.4b / 58112
• ZFINID: ZDB-GENE-000830-1
• Length: 307
• Species: Danio rerio
• Alignment Length: 275
• Identity: 63/275 - (22%)
• Similarity: 98/275 - (35%)
• Gaps: 81/275 - (29%)

  Fly    11 HQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQ-----------MNSNP----TTLNDH 60
            |.....:|....|:..:|.:....:..:..:|..|:|.:           ..|||    .|::..
Zfish    54 HSMSHNAYHMPHSQFSHSTMGGYCNGTIGAMGDLPSYQESMRNGATATAWYGSNPEPRYPTISRF 118

  Fly    61 CSPQHVHQQHVSSDENLPSQPNHDSQRVKL-------KRSRTAFTSVQLVELENEFKSNMYLYRT 118
            ..|        |:..|:.:.|..|:.:..:       ::.|..|:..|:.|||..||...||...
Zfish   119 MGP--------SAGMNMGTLPGMDASKSMVTLHAAPRRKRRVLFSQAQVYELERRFKQQKYLSAP 175

  Fly   119 RRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQ 183
            .|..:|..:.|...||||||||.|.|.|:                 ||:..|           ||
Zfish   176 EREHLASMIHLTPTQVKIWFQNHRYKMKR-----------------QAKDKA-----------SQ 212

  Fly   184 DPREGTAAAEKRPMMAVAPV-------------NPKPDYQASQKMKTEASTNNGMCSSADLSE-- 233
            ....|...|::.|.....||             .|.|.:|..|.:....:    :.|:.||.|
Zfish   213 QQDSGNMCAQQSPRRVALPVLVKDGKPCQNGSGTPTPIHQQVQSVLGSET----LASAEDLEEMS 273

  Fly   234 ----ILEHLAQTTAA 244
                ::..|:||.||
Zfish   274 PSPPLMGGLSQTDAA 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	23/55 (42%)
nkx2.4b	NP_571664.1	Homeodomain	148..204	CDD:459649	23/55 (42%)