Protein Alignment zen and NKX3-1

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_006158.2
• Gene: NKX3-1 / 4824
• HGNCID: 7838
• Length: 234
• Species: Homo sapiens
• Alignment Length: 161
• Identity: 49/161 - (30%)
• Similarity: 71/161 - (44%)
• Gaps: 36/161 - (22%)

  Fly    48 NQMNSNPTTLNDHCSPQHVH-------QQHVSS----DEN----LPSQPNHDSQRVKLKRSRTAF 97
            :|:::.|     ..:|:...       ::|:.|    .||    ||..|....|  ..||||.||
Human    74 DQLSTGP-----RAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQ--PQKRSRAAF 131

  Fly    98 TSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKK--------DIQGHRE 154
            :..|::|||.:|....||....|..:|:.|.|.|.||||||||||.|.|:        |::.|
Human   132 SHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKH-- 194

  Fly   155 PKSNAKLAQPQAEQSAHRGIVKRLMSYSQDP 185
                :.|...:.|..:...:|....||...|
Human   195 ----SSLPALKEEAFSRASLVSVYNSYPYYP 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	29/55 (53%)
NKX3-1	NP_006158.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..131		15/63 (24%)
		Homeodomain	125..181	CDD:459649	29/55 (53%)