Protein Alignment zen and cdx1

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 181
• Identity: 57/181 - (31%)
• Similarity: 84/181 - (46%)
• Gaps: 32/181 - (17%)

  Fly    16 GSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSDE----- 75
            |:.||:|:::.:|.      .|.||: .||....:   |.:||...||.....|..:..|
 Frog    80 GASSANPAQISFSP------SDYNPV-QPPGPGLL---PPSLNSSVSPLSPSAQRRNLYEWMRRT 134

  Fly    76 NLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQN 140
            .:|:..|.:.:.....:.|..:|..|.:|||.||..:.|:...|:.|:|..|:|.||||||||||
 Frog   135 GVPTSTNSNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAASLALTERQVKIWFQN 199

  Fly   141 RRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTAA 191
            ||.|         |.|.|.|..|.|::|::        .:....|..||.|
 Frog   200 RRAK---------ERKVNKKKMQQQSQQAS--------TTTPTPPSVGTTA 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	27/55 (49%)
cdx1	NP_989416.1	Caudal_act	13..141	CDD:461413	18/70 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		15/49 (31%)
		Homeodomain	151..206	CDD:459649	28/63 (44%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		8/20 (40%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		10/10 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		12/48 (25%)