Protein Alignment zen and NKX1-2

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001139812.1
• Gene: NKX1-2 / 390010
• HGNCID: 31652
• Length: 310
• Species: Homo sapiens
• Alignment Length: 86
• Identity: 41/86 - (47%)
• Similarity: 51/86 - (59%)
• Gaps: 5/86 - (5%)

  Fly    71 VSSDENLPSQPNHDSQRV-----KLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLC 130
            |.|....|..|....:|:     |.:|:|||||..|||.|||:|::..||....|:.:|..|||.
Human   139 VRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLT 203

  Fly   131 ERQVKIWFQNRRMKFKKDIQG 151
            |.||||||||||.|:||...|
Human   204 ETQVKIWFQNRRTKWKKQNPG 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	32/55 (58%)
NKX1-2	NP_001139812.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..165		6/25 (24%)
		Homeodomain	164..220	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..260		4/8 (50%)