DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zen and HOXD4

DIOPT Version :9

Sequence 1:	NP_476793.1	Gene:	zen / 40828	FlyBaseID:	FBgn0004053	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_055436.2	Gene:	HOXD4 / 3233	HGNCID:	5138	Length:	255	Species:	Homo sapiens

Alignment Length:	117	Identity:	51/117 - (43%)
Similarity:	68/117 - (58%)	Gaps:	12/117 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 HVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQV 134
            ||:|     ..||:...  :.||||||:|..|::|||.||..|.||.|.||||||..|.|.|||:
Human   141 HVNS-----VNPNYTGG--EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQI 198

  Fly   135 KIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIV--KRLMSYSQD 184
            ||||||||||:|||   |:.|.:..:.:...:..|....:.  :.|...::|
Human   199 KIWFQNRRMKWKKD---HKLPNTKGRSSSSSSSSSCSSSVAPSQHLQPMAKD 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeobox	93..146	CDD:278475	36/52 (69%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..127
		Antp-type hexapeptide	133..138
		Homeobox	157..210	CDD:306543	36/52 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..255		6/39 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810