Protein Alignment zen and HOXC8

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Alignment Length: 174
• Identity: 54/174 - (31%)
• Similarity: 81/174 - (46%)
• Gaps: 32/174 - (18%)

  Fly    13 AKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTT----LNDHCSPQHVHQQHVSS 73
            :|...|.|.|.:     .:||...:.:.:..|...:..|:|.:.    ||.:.||..:
Human    86 SKFYGYEALPRQ-----SLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLM------- 138

  Fly    74 DENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWF 138
               .|....|...|   :..|..::..|.:|||.||..|.||.|.||||::..|.|.||||||||
Human   139 ---FPWMRPHAPGR---RSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWF 197

  Fly   139 QNRRMKFKKD-----IQGHR-----EPKSNAKLAQPQAEQSAHR 172
            ||||||:||:     :.|.|     |.:.|.:..:.:.|:..::
Human   198 QNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENK 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	31/55 (56%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		9/52 (17%)
		Antp-type hexapeptide	138..143		1/14 (7%)
		Homeodomain	150..206	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		6/36 (17%)