DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zen and HOXB8

DIOPT Version :9

Sequence 1:	NP_476793.1	Gene:	zen / 40828	FlyBaseID:	FBgn0004053	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_076921.1	Gene:	HOXB8 / 3218	HGNCID:	5119	Length:	243	Species:	Homo sapiens

Alignment Length:	163	Identity:	54/163 - (33%)
Similarity:	77/163 - (47%)	Gaps:	29/163 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YYPV-HQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQH 70
            |.|: .|:..|  :.||..|:|:|....   ..:.:|.....::.:.:||.|.....||....:
Human    88 YDPLQRQSLFG--AQDPDLVQYADCKLA---AASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGR- 146

  Fly    71 VSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVK 135
                                :|.|..::..|.:|||.||..|.||.|.||||::..|.|.|||||
Human   147 --------------------RRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVK 191

  Fly   136 IWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQ 168
            |||||||||:||:....:.|.|  |..|.:.|:
Human   192 IWFQNRRMKWKKENNKDKFPSS--KCEQEELEK 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeobox	93..146	CDD:278475	31/52 (60%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		1/4 (25%)
		Homeobox	150..203	CDD:395001	31/52 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..243		6/22 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810