Protein Alignment zen and HOXB5

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 150
• Identity: 57/150 - (38%)
• Similarity: 70/150 - (46%)
• Gaps: 36/150 - (24%)

  Fly    33 GHHHDVNPIGLPPNYNQMNSNPTTLN----DHCS----PQHVHQQHVSSDENLPSQP-------- 81
            |..|...|....|: :|..|..::.|    |..|    |:....| :||.....:||
Human   105 GDSHGAKPSASSPS-DQATSASSSANFTEIDEASASSEPEEAASQ-LSSPSLARAQPEPMATSTA 167

  Fly    82 ------------------NHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLS 128
                              :||......||:|||:|..|.:|||.||..|.||.|.||||||..|.
Human   168 APEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 232

  Fly   129 LCERQVKIWFQNRRMKFKKD 148
            |.|||:||||||||||:|||
Human   233 LSERQIKIWFQNRRMKWKKD 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	37/55 (67%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	15/67 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		15/69 (22%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	37/55 (67%)