DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment zen and HOXB1

DIOPT Version :9

Sequence 1:NP_476793.1 Gene:zen / 40828 FlyBaseID:FBgn0004053 Length:353 Species:Drosophila melanogaster
Sequence 2:NP_002135.2 Gene:HOXB1 / 3211 HGNCID:5111 Length:301 Species:Homo sapiens


Alignment Length:178 Identity:62/178 - (34%)
Similarity:76/178 - (42%) Gaps:52/178 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 YYPVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQH------ 65
            |||:.|::.......||.       ||....    ||...|....:.|...    .|||      
Human    98 YYPLGQSEGDGGYFHPSS-------YGAQLG----GLSDGYGAGGAGPGPY----PPQHPPYGNE 147

  Fly    66 -------VHQQHVSSDEN--LPSQPNHDSQR----VKLKRS------------------RTAFTS 99
                   .:...:|.|:.  .||:||..:.|    :|:||:                  ||.||:
Human   148 QTASFAPAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTT 212

  Fly   100 VQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKK 147
            .||.|||.||..|.||.|.||:|||..|.|.|.||||||||||||.||
Human   213 RQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKK 260

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zenNP_476793.1 Homeobox 93..146 CDD:278475 35/70 (50%)
HOXB1NP_002135.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 20..77
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 127..149 5/25 (20%)
Antp-type hexapeptide 179..184 0/4 (0%)
Homeobox 207..259 CDD:278475 35/51 (69%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 254..301 6/7 (86%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.