DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zen and HOXA6

DIOPT Version :9

Sequence 1:	NP_476793.1	Gene:	zen / 40828	FlyBaseID:	FBgn0004053	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_076919.1	Gene:	HOXA6 / 3203	HGNCID:	5107	Length:	233	Species:	Homo sapiens

Alignment Length:	175	Identity:	58/175 - (33%)
Similarity:	74/175 - (42%)	Gaps:	60/175 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MHYYPVHQAKVGSYSA-------DPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCS 62
            :|:.|..|.|..|.|.       :.::.||:..:|            |...:|||        |:
Human   103 LHFSPEQQYKPDSSSGQGKALHDEGADRKYTSPVY------------PWMQRMNS--------CA 147

  Fly    63 PQHVHQQHVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRL 127
            .. |:..|.                   :|.|..:|..|.:|||.||..|.||.|.||||||..|
Human   148 GA-VYGSHG-------------------RRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANAL 192

  Fly   128 SLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKL---AQPQAEQS 169
            .|.|||:||||||||||:||:          .||   .||..|.|
Human   193 CLTERQIKIWFQNRRMKWKKE----------NKLINSTQPSGEDS 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeobox	93..146	CDD:278475	33/52 (63%)
HOXA6	NP_076919.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..127		6/23 (26%)
		Antp-type hexapeptide	136..141		2/16 (13%)
		Homeobox	159..212	CDD:365835	33/52 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	214..233		6/14 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810