Protein Alignment zen and HOXA5

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 192
• Identity: 65/192 - (33%)
• Similarity: 85/192 - (44%)
• Gaps: 50/192 - (26%)

  Fly     6 HYYPVHQAK--VGSYSADPSEVKYSDLIYGHHHDVNPIGLP-------PNYNQMNSNPTTL-NDH 60
            |:....:|:  ..|.||.|:|.:||..... .|...|..||       |..:..:....:| |..
Human    63 HFGSGERARSYAASASAAPAEPRYSQPATS-THSPQPDPLPCSAVAPSPGSDSHHGGKNSLSNSS 126

  Fly    61 CSPQHVHQQHVSSDENL---------------------------PSQP-----------NHDS-Q 86
            .:.......|:||.|.:                           |:||           :||: .
Human   127 GASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIG 191

  Fly    87 RVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKD 148
            ..:.||:|||:|..|.:|||.||..|.||.|.||||||..|.|.|||:||||||||||:|||
Human   192 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	37/55 (67%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		20/100 (20%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	196..252	CDD:459649	37/55 (67%)