Protein Alignment zen and TLX1

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: XP_011538046.1
• Gene: TLX1 / 3195
• HGNCID: 5056
• Length: 342
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 51/184 - (27%)
• Similarity: 70/184 - (38%)
• Gaps: 50/184 - (27%)

  Fly     9 PVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLP--------PNYNQ--------MNSNPTTL 57
            |.|:...|:.:               |......|||        |..|.        |.||....
Human   135 PAHRPLAGAVA---------------HPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESNRRYT 184

  Fly    58 NDH----CSPQHVHQQ--HVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLY 116
            .|.    .||..|.::  |...:...|          |.|:.||:||.:|:.|||..|....||.
Human   185 KDRFTVALSPFTVTRRIGHPYQNRTPP----------KKKKPRTSFTRLQICELEKRFHRQKYLA 239

  Fly   117 RTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHRE---PKSNAKLAQPQAE 167
            ...|..:|:.|.:.:.|||.||||||.|:::.....||   .::|..|.|.|.|
Human   240 SAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILLQLQQE 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	25/55 (45%)
TLX1	XP_011538046.1	Homeodomain	214..270	CDD:459649	25/55 (45%)