DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zen and hoxb8a

DIOPT Version :9

Sequence 1:	NP_476793.1	Gene:	zen / 40828	FlyBaseID:	FBgn0004053	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	XP_005171620.1	Gene:	hoxb8a / 30343	ZFINID:	ZDB-GENE-990415-108	Length:	246	Species:	Danio rerio

Alignment Length:	159	Identity:	56/159 - (35%)
Similarity:	77/159 - (48%)	Gaps:	31/159 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 QAKVGSYSADPSEVKYSD--LIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSD 74
            |...|:..||  .|:|||  |..|      .||...:..:.:.:||.|.....||      |::.
Zfish    95 QTLFGAQDAD--LVQYSDCKLATG------GIGDETDNTEQSPSPTQLFPWMRPQ------VAAG 145

  Fly    75 ENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQ 139
            .               :|.|..::..|.:|||.||..|.||.|.||||::..|.|.|||||||||
Zfish   146 R---------------RRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQ 195

  Fly   140 NRRMKFKKDIQGHREPKSNAKLAQPQAEQ 168
            |||||:||:....:.|.|.::..|.:.|:
Zfish   196 NRRMKWKKENNKDKFPSSKSEQEQIEKEK 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeobox	93..146	CDD:278475	31/52 (60%)
hoxb8a	XP_005171620.1	Homeobox	150..202	CDD:278475	31/51 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810