DRSC/TRiP Functional Genomics Resources

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Protein Alignment zen and hoxa2b

DIOPT Version :9

Sequence 1:NP_476793.1 Gene:zen / 40828 FlyBaseID:FBgn0004053 Length:353 Species:Drosophila melanogaster
Sequence 2:NP_571181.1 Gene:hoxa2b / 30325 ZFINID:ZDB-GENE-990415-98 Length:363 Species:Danio rerio


Alignment Length:330 Identity:95/330 - (28%)
Similarity:130/330 - (39%) Gaps:80/330 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 PSEVKYSDLIYGHH--HD---VNPIG--------LPPNY-----------NQMNSNPTTLND--- 59
            |.|.....|..|.|  |.   .||.|        |||.|           ||..|...|.:.   
Zfish    51 PFEQTIPSLNPGSHPRHSRPKQNPNGSCPLPAASLPPEYPWMKEKKASKKNQTTSTAATTDPGPL 115

  Fly    60 HCSPQHVHQQHVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIA 124
            :.|||             .|....|......:|.|||:|:.||:|||.||..|.||.|.||:|||
Zfish   116 YFSPQ-------------GSPEISDGGSGATRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA 167

  Fly   125 QRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGT 189
            ..|.|.|||||:||||||||.|:..|.......:.|  .|..|::..||             :|.
Zfish   168 ALLDLTERQVKVWFQNRRMKHKRQTQCKENHHGDGK--PPSLEEAGGRG-------------DGK 217

  Fly   190 AAAEKRPMMAVAPVNPKPDYQASQKMKTEASTNNGMCS---SADLSEI------LEH-------- 237
            :..|:........:..:..|...|...|...:.||..|   ||.:|.:      |:|        
Zfish   218 SFFEQVANNVSGALLEREGYPFQQNTLTSQQSQNGHNSDSQSATVSPLGSNDKHLKHFPNPSPTV 282

  Fly   238 -LAQTTAAPQVSTATSSTGTSTNSASSSSSGHYSYNVDLVLQSIKQDLEAAAQAWSKSKSAPI-L 300
             :..||.||..::|..:...|....|......:|.:..|.|.      :|.:.:.|:|..:|| |
Zfish   283 PICTTTMAPDCASAQDNGSPSALDVSLQDFNVFSNDSCLHLS------DAVSPSLSESVDSPIGL 341

  Fly   301 ATQSW 305
            .|:::
Zfish   342 TTEAF 346

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zenNP_476793.1 Homeobox 93..146 CDD:278475 35/52 (67%)
hoxa2bNP_571181.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..132 22/93 (24%)
Antp-type hexapeptide 88..93 1/4 (25%)
Homeobox 137..189 CDD:278475 35/51 (69%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 186..218 10/46 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 245..279 9/33 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 84 1.000 Inparanoid score I5154
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
54.860

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