DRSC/TRiP Functional Genomics Resources

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Protein Alignment zen and Pdx1

DIOPT Version :9

Sequence 1:NP_476793.1 Gene:zen / 40828 FlyBaseID:FBgn0004053 Length:353 Species:Drosophila melanogaster
Sequence 2:NP_074043.4 Gene:Pdx1 / 29535 RGDID:62387 Length:283 Species:Rattus norvegicus


Alignment Length:300 Identity:76/300 - (25%)
Similarity:109/300 - (36%) Gaps:114/300 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSSVMHYYPVHQ----------AKVGSYSADPSEVKY-----------------SDLIYGHHHDV 38
            |:|...||...|          ..|..:||:|....|                 ..|..|...|:
  Rat     1 MNSEEQYYAATQLYKDPCAFQRGPVPEFSANPPACLYMGRQPPPPPPPQFAGSLGTLEQGSPPDI 65

  Fly    39 NPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSDENLPSQ-----------PN-------HDS 85
            :|..:||           |.|..:..|:|       .:||:|           ||       .:.
  Rat    66 SPYEVPP-----------LADDPAGAHLH-------HHLPAQLGLAHPPPGPFPNGTETGGLEEP 112

  Fly    86 QRVKL-----------------------------KRSRTAFTSVQLVELENEFKSNMYLYRTRRI 121
            .||.|                             ||:|||:|..||:|||.||..|.|:.|.||:
  Rat   113 SRVHLPFPWMKSTKAHAWKSQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRV 177

  Fly   122 EIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLA---QPQAEQSAHRGIVKRLMSYSQ 183
            |:|..|:|.||.:||||||||||:||:....|...:.:...   :|:.:.:...|  :.|::...
  Rat   178 ELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRSSGTTSGGGGGEEPEQDCAVTSG--EELLALPP 240

  Fly   184 DPREGTAAAEKRPMMA-----------------VAPVNPK 206
            .|..|.|.....|..|                 :||:.|:
  Rat   241 PPPPGGAVPSGVPAAAREGRLPSGLSASPQPSSIAPLRPQ 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zenNP_476793.1 Homeobox 93..146 CDD:278475 32/52 (62%)
Pdx1NP_074043.4 Transactivation domain 13..73 11/70 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 36..81 9/55 (16%)
Antp-type hexapeptide 118..123 0/4 (0%)
Homeobox 149..203 CDD:395001 32/53 (60%)
Nuclear localization signal. /evidence=ECO:0000250 197..203 4/5 (80%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 201..283 14/81 (17%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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