Protein Alignment zen and Hoxd3

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001257967.1
• Gene: Hoxd3 / 288152
• RGDID: 1588601
• Length: 432
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 109/339 - (32%)
• Similarity: 145/339 - (42%)
• Gaps: 90/339 - (26%)

  Fly    39 NP-IGLP-------PNYNQMNSNPTTLNDHCSP------QHVHQQH--VSSDENL--PSQPNHDS 85
            || .|:|       ||   .:|:.:|::....|      |:..|::  .:|.||.  .|.|...|
  Rat   133 NPGSGVPAKKTKGGPN---ASSSSSTISKQIFPWMKESRQNSKQKNSCATSGENCEDKSPPGPAS 194

  Fly    86 QRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQ 150
            :||     |||:||.||||||.||..|.||.|.||:|:|..|:|.|||:||||||||||:|||
  Rat   195 KRV-----RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD-- 252

  Fly   151 GHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKM 215
                .|:...|..| |.||..|           .|..|.||........:.|| |...|.|....
  Rat   253 ----QKAKGILHSP-AGQSPER-----------SPPLGGAAGHVAYSGQLPPV-PGLAYDAPSPP 300

  Fly   216 KTEASTNN--GMCS-SADLSEILEHLAQTTAAPQVST-ATSSTGTSTNSASSSSS-----GHYSY 271
            ....|..|  |:.: :|.||..|.. .:..|||:... ..:|.|....||:...|     |::
  Rat   301 AFAKSQPNMYGLAAYTAPLSSCLPQ-QKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGGNF-- 362

  Fly   272 NVDLVLQSIKQDLEAAAQAWSKSKSAPI--LATQSWHPSSQS-------QVPTSVHAAPSMNLSW 327
                        :::.|.|     |.|:  |...| ||||.|       |:|.:.|..|.
  Rat   363 ------------VDSMAPA-----SGPVFNLGHLS-HPSSASVDYSCAAQIPGNHHHGPC----- 404

  Fly   328 GEPAAKSRKLSVNH 341
             :|......||.:|
  Rat   405 -DPHPTYTDLSAHH 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	36/55 (65%)
Hoxd3	NP_001257967.1	Homeodomain	195..251	CDD:459649	38/60 (63%)
		DUF4074	369..430	CDD:463833	18/61 (30%)