Protein Alignment zen and tlx1

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_739571.1
• Gene: tlx1 / 266964
• ZFINID: ZDB-GENE-021021-2
• Length: 301
• Species: Danio rerio
• Alignment Length: 286
• Identity: 64/286 - (22%)
• Similarity: 96/286 - (33%)
• Gaps: 104/286 - (36%)

  Fly     8 YPVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQH-----VH 67
            |..:...||||:.:                   :|...|.|.:||:....    .|.|     ||
Zfish    69 YNGNSCSVGSYNMN-------------------LGANVNGNCLNSSGVIR----VPAHRPLGSVH 110

  Fly    68 QQHVSSDENLPSQ--------------PNHDSQR-----------------------------VK 89
            ....:|...:||.              |..:|.|                             .|
Zfish   111 SSIPTSAATVPSMGSMGTINNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPK 175

  Fly    90 LKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHRE 154
            .|:.||:||.:|:.|||..|....||....|..:|:.|.:.:.|||.||||||.|:::.....||
Zfish   176 KKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEERE 240

  Fly   155 PKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEA 219
            .:          .|.|:|    .||...|:..:.|..         .||.|.|          ..
Zfish   241 AE----------RQQANR----ILMQLQQEAFQKTIN---------QPVTPDP----------IC 272

  Fly   220 STNNGMCSSADLSEILEHLAQTTAAP 245
            ..|:.:.:..:|....|:.|:.::.|
Zfish   273 LHNSSLFALQNLQPWTENTAKISSVP 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	25/55 (45%)
tlx1	NP_739571.1	Homeodomain	177..233	CDD:459649	25/55 (45%)