DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zen and GBX2

DIOPT Version :9

Sequence 1:	NP_476793.1	Gene:	zen / 40828	FlyBaseID:	FBgn0004053	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_001476.2	Gene:	GBX2 / 2637	HGNCID:	4186	Length:	348	Species:	Homo sapiens

Alignment Length:	119	Identity:	50/119 - (42%)
Similarity:	59/119 - (49%)	Gaps:	26/119 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 SSDENLPSQ-------PNHDSQRV--------------KLKRSRTAFTSVQLVELENEFKSNMYL 115
            |||:||..|       |.|..:..              |.:|.||||||.||:|||.||....||
Human   208 SSDDNLTGQAAHKEEDPGHALEETPPSSGAAGSTTSTGKNRRRRTAFTSEQLLELEKEFHCKKYL 272

  Fly   116 YRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHR-----EPKSNAKLAQP 164
            ..|.|.:||..|.|.|.||||||||||.|:|:...|:.     ||..|.|:..|
Human   273 SLTERSQIAHALKLSEVQVKIWFQNRRAKWKRVKAGNANSKTGEPSRNPKIVVP 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeobox	93..146	CDD:278475	33/52 (63%)
GBX2	NP_001476.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	59..81
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	111..139
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..251		10/42 (24%)
		Homeobox	250..303	CDD:306543	33/52 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810