Protein Alignment zen and NKX2-8

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 189
• Identity: 59/189 - (31%)
• Similarity: 77/189 - (40%)
• Gaps: 32/189 - (16%)

  Fly    72 SSDE-NLPSQPNHDSQR------------VKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEI 123
            |||| :|.:.|...|||            .|.|:.|..|:..|.:|||..|:...||....|.::
Human    53 SSDESSLETSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQL 117

  Fly   124 AQRLSLCERQVKIWFQNRRMKFKK-DIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDP-- 185
            |..|.|...||||||||.|.|.|: ...|..|....|..|:..|.....|.:|..::.....|
Human   118 ASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLVRDGQPCG 182

  Fly   186 -----REGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEASTNNGMCSSADLSEILEHLA 239
                 ..|||||:::.....|...|.|.|.|.           |..|:..|....:|||
Human   183 GGGGGEVGTAAAQEKCGAPPAAACPLPGYPAF-----------GPGSALGLFPAYQHLA 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	24/55 (44%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		11/33 (33%)
		Homeodomain	85..141	CDD:459649	24/55 (44%)