Protein Alignment zen and EVX1

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 66/267 - (24%)
• Similarity: 95/267 - (35%)
• Gaps: 81/267 - (30%)

  Fly    61 CSPQHVHQQHV--SSDENLPSQPNHDSQRVK---------------------LKRSRTAFTSVQL 102
            |:..:...||.  |..|.|...||..|:..|                     ::|.|||||..|:
Human   131 CATGNAEYQHSKGSGSEALVGSPNGGSETPKSNGGSGGGGSQGTLACSASDQMRRYRTAFTREQI 195

  Fly   103 VELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKD-----------------IQ 150
            ..||.||....|:.|.||.|:|..|:|.|..:|:||||||||.|:.                 :.
Human   196 ARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMM 260

  Fly   151 GHR-------------------EPKSNAKLAQPQAEQSAHRGIVKRLMSY---SQD-PREGTAAA 192
            .|.                   .|......:...|..|...|.::.|.::   ||. ||.....|
Human   261 SHAAAAGGLPYPFPSHLPLPYYSPVGLGAASAASAAASPFSGSLRPLDTFRVLSQPYPRPELLCA 325

  Fly   193 EKRPMMAVAPVNPKPDYQASQKMKTEASTNNGMCSSADLSEILEHLAQTTA-APQVSTATSSTGT 256
            .:.|     |:.|.|.:..       .::..|.||.     :..|...... ||:.:.|:..|..
Human   326 FRHP-----PLYPGPAHGL-------GASAGGPCSC-----LACHSGPANGLAPRAAAASDFTCA 373

  Fly   257 STNSASS 263
            ||:.:.|
Human   374 STSRSDS 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	29/55 (53%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		9/41 (22%)
		Homeodomain	184..240	CDD:459649	29/55 (53%)