Protein Alignment zen and Nkx1-2

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_033149.1
• Gene: Nkx1-2 / 20231
• MGIID: 104806
• Length: 305
• Species: Mus musculus
• Alignment Length: 160
• Identity: 56/160 - (35%)
• Similarity: 72/160 - (45%)
• Gaps: 21/160 - (13%)

  Fly    72 SSDENLPSQPNH-----------DSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQ 125
            |..|.||:.|..           :|...|.:|:|||||..|||.|||:|::..||....|:.:|.
Mouse   127 SGAEGLPASPGSPGSPRPRRRRAESSCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLAL 191

  Fly   126 RLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTA 190
            .|||.|.||||||||||.|:||...|    ...|..|...|.|....|.|      :......|.
Mouse   192 SLSLTETQVKIWFQNRRTKWKKQNPG----ADGAVQAGGGAPQPGTPGAV------AGGGGSATG 246

  Fly   191 AAEKRPMMAVAPVNPKPDYQASQKMKTEAS 220
            ::...|:....|....|.|.|:..:...||
Mouse   247 SSPGPPVPGALPYQTFPTYPATNVLFPAAS 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	32/55 (58%)
Nkx1-2	NP_033149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..158		7/30 (23%)
		Homeodomain	157..213	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..257		12/56 (21%)