Protein Alignment zen and EMX1

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 153
• Identity: 48/153 - (31%)
• Similarity: 66/153 - (43%)
• Gaps: 21/153 - (13%)

  Fly     8 YPVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVS 72
            :|.||     ..|.|.:..:|  .:|..|          .:.::..|..|.:...........|.
Human   131 HPAHQ-----LGASPLQPPHS--FFGAQH----------RDPLHFYPWVLRNRFFGHRFQASDVP 178

  Fly    73 SDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIW 137
            .|..|    .|.....|.||.||||:..||:.||..|:.|.|:....|.::|..|||.|.|||:|
Human   179 QDGLL----LHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVW 239

  Fly   138 FQNRRMKFKKDIQGHREPKSNAK 160
            |||||.|:|:.......|:|..|
Human   240 FQNRRTKYKRQKLEEEGPESEQK 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	29/55 (53%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		3/14 (21%)