Protein Alignment zen and GSX2

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_573574.2
• Gene: GSX2 / 170825
• HGNCID: 24959
• Length: 304
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 69/249 - (27%)
• Similarity: 95/249 - (38%)
• Gaps: 105/249 - (42%)

  Fly    16 GSYSADPSEVKYSDLI-YGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSDENLPS 79
            |.:|:.|.:.::...: :.|||                       |..|||.|..|      .|.
Human   107 GQFSSAPGDAQFCPRVNHAHHH-----------------------HHPPQHHHHHH------QPQ 142

  Fly    80 QP-------------------------------------------------NHDSQRVKLKRSRT 95
            ||                                                 :..||....||.||
Human   143 QPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTYNVADPRRFHCLTMGGSDASQVPNGKRMRT 207

  Fly    96 AFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAK 160
            ||||.||:|||.||.|||||.|.||||||..|:|.|:||||||||||:|.||:.:|
Human   208 AFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKG--------- 263

  Fly   161 LAQPQAEQSAHRG--IVKRLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQAS 212
                 .::::|.|  .|...:.|::...|.          :::|.:...|.:.|
Human   264 -----TQRNSHAGCKCVGSQVHYARSEDED----------SLSPASANDDKEIS 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	41/55 (75%)
GSX2	NP_573574.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..151		12/63 (19%)
		Homeodomain	203..259	CDD:459649	41/55 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..304		4/30 (13%)