Protein Alignment zen and NKX6-3

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_001351770.1
• Gene: NKX6-3 / 157848
• HGNCID: 26328
• Length: 265
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 56/207 - (27%)
• Similarity: 80/207 - (38%)
• Gaps: 50/207 - (24%)

  Fly     8 YPVHQAKVGSYSADPSEVKYS------DLIYGHHHDV-----NPIGLPPNYNQMNSNP------- 54
            :|..:|.|..||...|..|.|      .|..|..|.:     .|:. .||.:.::..|
Human    19 FPEMKAPVCQYSVQNSFYKLSPPGLGPQLAAGTPHGITDILSRPVA-APNNSLLSGYPHVAGFGG 82

  Fly    55 -TTLNDHCSPQHVHQQHVSSD----------------------ENLPSQPNHDSQRVKLKRSRTA 96
             ::...:.|||..:.....::                      .|.| .|..||.. |.|.:|..
Human    83 LSSQGVYYSPQVGNFSKAGNEYPTRTRNCWADTGQDWRGGRQCSNTP-DPLSDSIH-KKKHTRPT 145

  Fly    97 FTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKL 161
            ||..|:..||..|:...||....|..:|..|.:.|.|||:||||||.|::|  :...||.|:.
Human   146 FTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK--KSALEPSSST-- 206

  Fly   162 AQPQAEQSAHRG 173
              |:|...|..|
Human   207 --PRAPGGAGAG 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	24/55 (44%)
NKX6-3	NP_001351770.1	Homeodomain	138..196	CDD:459649	25/57 (44%)