Protein Alignment zen and Hoxd8

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_032302.2
• Gene: Hoxd8 / 15437
• MGIID: 96209
• Length: 289
• Species: Mus musculus
• Alignment Length: 148
• Identity: 50/148 - (33%)
• Similarity: 73/148 - (49%)
• Gaps: 29/148 - (19%)

  Fly    41 IGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVEL 105
            ||..|::...:|:|:.:.....||              :.|..       :|.|..::..|.:||
Mouse   167 IGEDPDHLNQSSSPSQMFPWMRPQ--------------AAPGR-------RRGRQTYSRFQTLEL 210

  Fly   106 ENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSA 170
            |.||..|.||.|.||||::..|:|.||||||||||||||:||:....:.|.|     :|:|:...
Mouse   211 EKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQNRRMKWKKENNKDKFPAS-----RPEAKDGD 270

  Fly   171 HRGIVKRLMSYSQDPREG 188
            .:   |.:....:|..||
Mouse   271 PK---KEVSGLEEDGAEG 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	32/55 (58%)
Hoxd8	NP_032302.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..125
		COG5576	139..272	CDD:227863	46/130 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..184		5/16 (31%)
		Antp-type hexapeptide	183..188		0/4 (0%)
		Homeodomain	196..252	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..289		9/42 (21%)