Protein Alignment zen and Hoxd3

DIOPT Version :9

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_034598.2
• Gene: Hoxd3 / 15434
• MGIID: 96207
• Length: 433
• Species: Mus musculus
• Alignment Length: 341
• Identity: 96/341 - (28%)
• Similarity: 136/341 - (39%)
• Gaps: 76/341 - (22%)

  Fly     9 PVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSS 73
            |..:.| |..||..|....|..|:....:..     .|..|.||..|: .::|..:
Mouse   140 PAKKTK-GGLSASSSSSTISKQIFPWMKESR-----QNSKQKNSCATS-GENCEDK--------- 188

  Fly    74 DENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWF 138
                 |.|...|:||     |||:||.||||||.||..|.||.|.||:|:|..|:|.|||:||||
Mouse   189 -----SPPGPASKRV-----RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWF 243

  Fly   139 QNRRMKFKKDIQG----HREPKSNAKLAQP---QAEQSAHRGIVKRLMSYSQDPREGTAAAEKRP 196
            ||||||:|||.:.    |.....:.:.:.|   .|...|:.|.:..:...:.|.....|.|:.:|
Mouse   244 QNRRMKYKKDQKAKGILHSPAGQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQP 308

  Fly   197 MM-----AVAPVN---------PKPDYQASQKMKTEASTNNGMCSSADLSEILEHLAQTTAAPQV 247
            .|     ..||::         |.|:::..     ..::|.|..:||:|.          .:|..
Mouse   309 NMYGLAAYTAPLSSCLPQQKRYPAPEFEPH-----PMASNGGGFASANLQ----------GSPVY 358

  Fly   248 STATSSTGTSTNSASSSSSGHYSYNVDLVLQSIKQDLEAAAQAWSKSKSA-----PILATQSWHP 307
            .........:..|....:.||.|:.     .|...|...|||........     |.....|.|.
Mouse   359 VGGNFVDSMAPTSGPVFNLGHLSHP-----SSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHH 418

  Fly   308 SSQSQVPTSVHAAPSM 323
            |||.::|    .||.:
Mouse   419 SSQGRLP----EAPKL 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeobox	93..146	CDD:278475	36/52 (69%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..198		17/78 (22%)
		Antp-type hexapeptide	161..166		1/4 (25%)
		Homeobox	199..251	CDD:278475	36/51 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..280		3/21 (14%)
		DUF4074	370..431	CDD:290032	18/70 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..433		9/34 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.770