DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zen and Hoxd1

DIOPT Version :9

Sequence 1:	NP_476793.1	Gene:	zen / 40828	FlyBaseID:	FBgn0004053	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_034597.2	Gene:	Hoxd1 / 15429	MGIID:	96201	Length:	328	Species:	Mus musculus

Alignment Length:	196	Identity:	60/196 - (30%)
Similarity:	82/196 - (41%)	Gaps:	53/196 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VHQAKVGSYSADPSEVKYSDLIYGHHHDVNPI---------GLPPNYNQMNSNPTTLNDHCSPQH 65
            ||.|....:|...|.:....:.:....:..|.         |.|..:..::..|.......||
Mouse   132 VHYATSAVFSGGGSFLLSGQVDFAAFGEPGPFPACLKEPADGHPGPFQTVSPAPGACPKPASP-- 194

  Fly    66 VHQQHVSSDENLPSQPNHDS-QRVKLKRS-------------------RTAFTSVQLVELENEFK 110
                    ..:||:.  |.: :.:|:||:                   ||.|::.||.|||.||.
Mouse   195 --------TSSLPAA--HSTFEWMKVKRNAPKKSKLSEYGATSPPSAIRTNFSTKQLTELEKEFH 249

  Fly   111 SNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPK-------SNAKLAQPQAEQ 168
            .|.||.|.||||||..|.|.:.||||||||||||.||     ||.:       |.|.:..|::|.
Mouse   250 FNKYLTRARRIEIANCLQLNDTQVKIWFQNRRMKQKK-----REREGLLATAASVASIKLPRSET 309

  Fly   169 S 169
            |
Mouse   310 S 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeobox	93..146	CDD:278475	34/71 (48%)
Hoxd1	NP_034597.2	PRK04233	59..>105	CDD:305134
		Antp-type hexapeptide	204..209		0/4 (0%)
		Homeobox	233..285	CDD:278475	34/51 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	304..328		3/7 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810