DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment zen and Hoxc5

DIOPT Version :9

Sequence 1:NP_476793.1 Gene:zen / 40828 FlyBaseID:FBgn0004053 Length:353 Species:Drosophila melanogaster
Sequence 2:NP_783857.1 Gene:Hoxc5 / 15424 MGIID:96196 Length:222 Species:Mus musculus


Alignment Length:192 Identity:66/192 - (34%)
Similarity:80/192 - (41%) Gaps:62/192 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 GSYSADPSEVKYSDLIYGHHHDVNPIGLPP-------NYNQMNSNPTTLNDH--CSPQHVHQQHV 71
            |:|.: .|||:.|...|| ..|:: |..||       :...|.:||....|.  ||........:
Mouse    25 GNYGS-ASEVQASRYCYG-GLDLS-ITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPGHAL 86

  Fly    72 SSDENLPSQPNHDSQR------------------------------------------VKL---- 90
            ..||..|..|...||:                                          .||    
Mouse    87 GRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPWMTKLHMSH 151

  Fly    91 ----KRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKD 148
                |||||::|..|.:|||.||..|.||.|.||||||..|.|.|||:||||||||||:|||
Mouse   152 ETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRMKWKKD 213

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zenNP_476793.1 Homeobox 93..146 CDD:278475 35/52 (67%)
Hoxc5NP_783857.1 COG5373 65..>142 CDD:227665 11/76 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 68..141 9/72 (13%)
Antp-type hexapeptide 140..145 0/4 (0%)
Homeobox 158..212 CDD:395001 35/53 (66%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.900

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