DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zen and Mnx1

DIOPT Version :9

Sequence 1:	NP_476793.1	Gene:	zen / 40828	FlyBaseID:	FBgn0004053	Length:	353	Species:	Drosophila melanogaster
Sequence 2:	NP_064328.2	Gene:	Mnx1 / 15285	MGIID:	109160	Length:	404	Species:	Mus musculus

Alignment Length:	266	Identity:	81/266 - (30%)
Similarity:	115/266 - (43%)	Gaps:	72/266 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SVMHYYPVHQAKVGSYSADPS---------EVKYS-DLIYGHH--HDVNPIGLPPNYNQMNSNPT 55
            :.::.:||:     ||||..:         .:.|| ..:.|.|  |..:||.|..:..|::
Mouse   156 AALYGHPVY-----SYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGASTFQLD---- 211

  Fly    56 TLNDHCSPQHVHQQHVSSDENLPSQPNHDSQRV-----KLKRSRTAFTSVQLVELENEFKSNMYL 115
                    |.:...  ::...||..|:..||..     |.:|.||||||.||:|||::||.|.||
Mouse   212 --------QWLRAS--TAGMILPKMPDFSSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYL 266

  Fly   116 YRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHR------GI 174
            .|.:|.|:|..|.|.|.||||||||||||:|:           :|.|:.||.|.|.:      |.
Mouse   267 SRPKRFEVATSLMLTETQVKIWFQNRRMKWKR-----------SKKAKEQAAQEAEKQKGGGGGT 320

  Fly   175 VK---------RLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEASTNNGM----- 225
            .|         .||.   .|..|..|:.:| :..:...:|..|....::.....|...|.
Mouse   321 GKGGSEEKTEEELMG---PPVSGDKASGRR-LRDLRDSDPDEDEDDEEEDNFPYSNGAGAHAASS 381

  Fly   226 -CSSAD 230
             |||.|
Mouse   382 DCSSED 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeobox	93..146	CDD:278475	35/52 (67%)
Mnx1	NP_064328.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..80
		Homeobox	244..297	CDD:278475	35/52 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	299..404		22/93 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810