Protein Alignment zen and Dlx3

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_034185.1
• Gene: Dlx3 / 13393
• MGIID: 94903
• Length: 287
• Species: Mus musculus
• Alignment Length: 226
• Identity: 63/226 - (27%)
• Similarity: 95/226 - (42%)
• Gaps: 53/226 - (23%)

  Fly    15 VGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVH-------QQHVS 72
            :|.||| |....||...||  ..|||.   ..::|.|.|........||:..:       |....
Mouse    40 LGYYSA-PQHDYYSGQPYG--QTVNPY---TYHHQFNLNGLAGTGAYSPKSEYTYGGSYRQYGAY 98

  Fly    73 SDENLPSQ--------PNHDSQRV-----KLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIA 124
            .::.||:|        |..:.:.|     |:::.||.::|.||..|:..|:...||....|.|:|
Mouse    99 REQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELA 163

  Fly   125 QRLSLCERQVKIWFQNRRMKFKK-----DIQGHREPKSNAKLA--QPQA----EQSAHRGIVKRL 178
            .:|.|.:.||||||||||.||||     ::.....|.::..:|  .|.:    :.|:|
Mouse   164 AQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSH------- 221

  Fly   179 MSYSQDPREGTAAAEKRPMMAVAPVNPKPDY 209
                     .|.|..:.|:....|.:..|:|
Mouse   222 ---------STPAPARNPLPPPLPYSASPNY 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	26/55 (47%)
Dlx3	NP_034185.1	DLL_N	27..107	CDD:463567	20/72 (28%)
		COG5576	<109..224	CDD:227863	36/130 (28%)
		Homeodomain	130..186	CDD:459649	26/55 (47%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:O60479	131..181		22/49 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..287		11/65 (17%)