Protein Alignment zen and Cdx1

DIOPT Version :10

• Sequence 1: NP_476793.1
• Gene: zen / 40828
• FlyBaseID: FBgn0004053
• Length: 353
• Species: Drosophila melanogaster
• Sequence 2: NP_034010.3
• Gene: Cdx1 / 12590
• MGIID: 88360
• Length: 268
• Species: Mus musculus
• Alignment Length: 213
• Identity: 57/213 - (26%)
• Similarity: 80/213 - (37%)
• Gaps: 50/213 - (23%)

  Fly    17 SYSADP--SEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSDENLPS 79
            :|...|  |....:.|.:|...|.:|:..||     ...|..|     .|.:......|....|.
Mouse    75 AYGPGPTASAASPAPLAFGPPPDFSPVPAPP-----GPGPGIL-----AQSLGAPGAPSSPGAPR 129

  Fly    80 QPNHD-------------SQRVKLK-RSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLC 130
            :..::             |.:.:.| :.|..:|..|.:|||.||..:.|:...|:.|:|..|.|.
Mouse   130 RTPYEWMRRSVAAAGGGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLT 194

  Fly   131 ERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTAAAEKR 195
            ||||||||||||.|         |.|.|.|..|.|.....         :....|.:||......
Mouse   195 ERQVKIWFQNRRAK---------ERKVNKKKQQQQQPLPP---------TQLPLPLDGTPTPSGP 241

  Fly   196 PMMAVAPVN------PKP 207
            |:.::.|.|      |.|
Mouse   242 PLGSLCPTNAGLLGTPSP 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
zen	NP_476793.1	Homeodomain	91..147	CDD:459649	28/56 (50%)
Cdx1	NP_034010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		15/86 (17%)
		Caudal_act	13..140	CDD:461413	14/74 (19%)
		Homeodomain	156..211	CDD:459649	28/63 (44%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	157..178		8/20 (40%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	196..207		10/10 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..268		14/60 (23%)